HBOT and Head Injury
"Hyperbaric Oxygen Therapy (HBOT) for Reduction of Secondary Brain Damage in Head Injury"
—Journal of Neurotrauma, 21:44-48. 2004
Conclusion: Translational research of HBOT in a variety of Traumatic Brain Injuries (TBI) models has shown neuroprotective effects
in the absence of increased oxygen toxicity. Recent clinical trials favour HBOT as promising safe therapeutic strategy for severe TBI patient.

Role of Hyperbaric Oxygen Therapy in Severe Head Injury in Children
—Journal of Pediatric Neuroscience. 2012 Jan-April 7(1) 4-8
Conclusion: In children with traumatic brain injury, the addition of HBOT significantly improved outcome and quality of life and reduced risk of complications. Patients receiving HBOT were significantly better than the control group with decreased hospital stay, better Glasgow Coma Scale and drastic reduction in disability.

Hyperbaric Oxygen Therapy can improve Post Concussion Syndrome years after Mild Traumatic Brain Injury - Randomised Prospective Trial
—PLoS One November 2013 10.137/journal.pone 0079995
Conclusion: Convincing results based on a crossover study, demonstrating that HBOT can induce neuroplasticity and significant brain function improvement in mild TBI patients with prolonged Post-Concussion-Syndrome at late chronic stage, years after injury.

The findings here bear the promises that HBOT can be effective in treating other brain impairments like PTSD or repairing radiation damage. It is reasonable to expect that HBOT can help slow down or even reverse metabolic disorders associated with neurodegenerative diseases.

HBOT and Sports Injury
Effects of Exposure to Hyperbaric Oxygen for the Treatment of Acute Soft Tissue Injury”
—Clinical Journal of Sports Medicine 13 (3): 138-147. 2003.
Conclusion: In many cases of sports injury, surgery is often required. Treatments that can speed up the healing process are of greatest interest to the patient and the doctors. The advantages of HBOT are the known benefits in reducing swelling, decreased inflammation, improved collagen deposition in the skin and increasing the growth of new blood cells.

Hyperbaric Oxygen Therapy in Sports Injury
—Journal of Applied Physiology 106 (2): 711-728 2009.
Conclusion: By coupling the advances in sports medicine, physical treatments and Hyperbaric medicine, we will accelerate
the time to recovery, complement surgical procedures and enhance the outcomes of physical therapy. As many professional sports teams have discovered, HBOT is a real tool to enhance their performance and reduce their down-time from injuries.

HBOT in Stroke and Wound Repair
Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients – Randomised Prospective Trial
—University of Muster, Germany. January 2013
Conclusion: The clinical results indicate that HBOT can lead to significant neurological improvements in post stroke patients, even at chronic late stage. The observed clinical improvements indicate that neuroplasticity can still be activated long after damage onset.

Oxygen in Wound Healing: nutrient, antibiotic, signalling molecule and therapeutic agent
—Clinical Plastic Surgery July 2012 39(3) 293-310
Conclusion: There is strong scientific basis for oxygen treatment as prophylaxis against infection, to facilitate wound closure. This article reviews extensive data from human trials of hyperbaric oxygen and topical oxygen treatment. Oxygen supports biochemical metabolism and cellular function and has roles in combating infection and facilitating the wound healing cascade.

HBOT and Cancer
Hyperbaric Oxygen Therapy and Cancer – a review
—Target Oncology 2012 Dec; 7(4): 233-242
Conclusion: Two systematic reviews have concluded that the use of HBOT in patients with malignancies is considered safe. HBOT alone has a strong anti proliferative effect on different mammary cells in vivo and vitro. HBOT could be an effective therapy for breast cancer and this is supported by six studies over the last nine years.

HBOT and Acute Myocardial Infarction (heart attack)
Hyperbaric Oxygen and Thrombolysis in Myocardial Infarction
—The American Heart Journal, September 1998.
Conclusion: Hyperbaric Oxygen Treatment (HBOT) in combination with thrombolysis has been demonstrated to salvage myocardium in acute myocardial infarction (AMI). Treatment with HBOT appears to be a feasible and safe treatment for AMI and may result in an attenuated rise in creatine phosphokinase and a more rapid resolution of pain.

HBOT and Inflammatory Bowel Disease
Hyperbaric Oxygen Treatment for Inflammatory Bowel Disease: a Systematic Review and Analysis
—Journal of Medical Gastroenterology. March 2013.
Conclusion: In patients with Crohn’s Disease, 78% had clinical improvements, while all 39 patients with ulcerative colitis improved.

HBOT lowered markers of inflammation and oxidative stress and ameliorated inflammatory bowel disease in both human and animal studies.

HBOT and Fibromyalgia
Hyperbaric Oxygen can diminish fibromyalgia syndrome – prospective clinical trial”
—PLoS One.2015;10(5)e0127012. PubMed
Conclusion: The study provides evidence that HBOT can improve the symptoms and life quality of FMS patients. Moreover it shows that HBOT can induce neuroplasticity and significantly rectify abnormal brain activity in pain related areas of FMS patients.

HBOT for Diabetes and Obesity
Effects of Hyperbaric Oxygen on metabolic capacity of the skeletal muscle in Type II diabetic rats with obesity
—Scientific World Journal 2012.
Conclusion: Hyperbaric Oxygen enhances glucose and lipid metabolism in the skeletal muscle, indicating that HBOT can prevent elevation of glucose and adipocyte hypertrophy.

HBOT and Recovery from Surgery
Applications of Hyperbaric Oxygen Therapy and Surgery
—Division of Surgery, University of Nevada School of Medicine, Nevada, USA. 1992.
Conclusion: Many factors can delay wound healing such as oedema, infection, anaemia, poor perfusion and poor oxygen supply. The consequences of these factors is low oxygen tension, which adversely affects neutrophil, macrophages, collagen synthesis and fibroblast function during inflammation and repair. Hyperbaric Oxygen Therapy successfully negates these problems.

HBOT and Infertility
Hyperbaric Oxygenation as a possible therapy of choice for infertility treatment”
—Bosn Journal Basic Medical Science 2006 May: 6(2):21-4.PubMed
Conclusion: The oxygen used under pressure, the oxygen as a drug may have extraordinary significance for better outcome of pregnancy implantation by improving endometrial receptivity. If endometrial receptivity is conditioned by adequate vascularisation and oxygenation, then hyperbaric oxygen is the treatment of choice.

HBOT for Children

How mild Hyperbaric Oxygen Therapy (mHBOT) worked and why it's good for our children”
—Medicinal Veritas, 2 647. 2005.
Conclusion: Children on the autistic spectrum experience improvement in a wide range of their symptoms with mHBOT treatments, including increased language ability, better socialisation, less aggression, improved bowel function and better cognition, to name a few.